Amifru Plus Tablet is a combination of two medicines used to reduce excess fluid levels in the body. It is used to treat edema (fluid overload) and some cases of hypertension. It is best to take Amifru Plus Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time everyday. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Nausea, vomiting, diarrhea, and dehydration are very common side effect of this medicine. It might lower down the level of calcium, sodium and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It might cause dizziness or tiredness, if happens rise slowly from sitting position or avoid driving. Before taking this medicine, tell your doctor if you have any liver or kidney disease. It is generally safe to use during pregnancy or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.