Calembic 150 mg/225 mg Tablet is a combination of two medicines. This medicine is prescribed to treat osteoporosis. It prevents bone loss and helps in thickening of the bones. This is how it prevents fractures. Calembic 150 mg/225 mg Tablet is best taken in an empty stomach. You should take it regularly at a fixed time each day. Taking it at the same time every day will help you remember to take it. It may take several days to get the full benefit of this drug. Do not stop taking it until you have finished the dose. This medicine may only be part of a treatment program that may also include changes to your diet and taking other medicines and vitamin supplements. The most common side effects of this medicine include headache, back pain, musculoskeletal (bone, muscle or joint) pain, indigestion, diarrhea, and heartburn. These are generally mild and usually resolve on their own. If they do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects. Before using this medicine, let your doctor know if you have any medical conditions or disorders. To make sure the medicine is safe for you, let your doctor also know all the other medicines you are taking. You may need frequent medical tests to check your kidney function and mineral levels while on treatment with this medicine. You should avoid consuming large amounts of alcohol, as it can cause bone loss. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.