Depiluk Cream is a prescription medicine having a combination of medicines that are used to treat melasma. It helps in brightening of the skin. It prevents premature ageing and reduces wrinkles. Depiluk Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only. Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies from this medicine. Usually, this medicine is well tolerated and has minimal side effects like dry skin, skin rashes, etc. If these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please consult your doctor. Inform your doctor if you are pregnant or breastfeeding or are suffering from any other disease.