Deplam 0.25 mg/25 mg Tablet is a prescription medicine used in the treatment of depression. It is a combination medicine that calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also increases the level of chemical messengers in the brain that help in regulating mood. Deplam 0.25 mg/25 mg Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may cause withdrawal symptoms. Some common side effects of this medicine include constipation, difficulty in urination, dryness in mouth, weight gain, confusion, and memory impairment. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Most of the comm effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Some common side effects of this medicine include memory impairment, dryness in mouth, blurred vision, increased heart rate, constipation, depression and confusion. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you.