Dobipile Plus 500mg/500mg Tablet is a medicine used to treat piles. Dobipile Plus 500mg/500mg Tablet is a combination of two medicines that helps to promote healing. Dobipile Plus 500mg/500mg Tablet should be taken with or without food at a fixed time every day to get the most benefits. The dose depends on what you are taking it for and the severity of your condition. Keep taking it for as long as advised by your doctor. Follow your doctor’s advice while taking this medicine. Diarrhea is a very common side effect of this medicine. Drink plenty of fluids or consult with your doctor if it does not go away. Let your doctor know if you notice muscle weakness or decrease in urination and dark color urination. Other than this, nausea, skin rash, fever, and headache may also occur as side effects. Before taking this medicine, tell your doctor if you have liver or kidney disease. Tell your doctor about pregnancy or breastfeeding before taking this medicine. Your doctor also needs to know what other medicines you are taking as there are many which interact with this medicine and affect the way it works.