Donrid O 4mg/10mg Tablet is a combination of medicine used in the treatment of nausea and vomiting. It also relieves symptoms such as heartburn, indigestion, stomach pain, or irritation by reducing the production of acid in the stomach. Donrid O 4mg/10mg Tablet is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are diarrhea, stomach pain, constipation, flatulence, headache, and fatigue. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. To overcome constipation, you should add fibre-rich foods in your diet and stay hydrated. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver or kidney diseases so that your doctor can prescribe a suitable dose for you.