Estram 140mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy. Estram 140mg Capsule should be taken on an empty stomach. The calcium in the stomach might affect the working of drug, so better to avoid milk, dairy products such as cheese and avoid taking it in combination with an antacid or other medicine containing calcium, magnesium or aluminum. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), increased liver enzymes and fluid retention. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood, liver function and the level of calcium in your blood. Before taking it, tell your doctor if have heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.