Fisofine Cream is a combination of two medicines used in the treatment of anal fissures (tear in the lining of the anus). It relieves the pain, swelling, itching, and discomfort associated with passing of stools in people who suffer from problems in the anal area. Fisofine Cream relaxes the blood vessels in the anus thus helping in the healing of anal fissures. It should be used in the dose and duration as directed by your doctor. Clean and dry the affected area before applying this medicine. Make sure to wash your hands thoroughly before and after applying this medicine. Do not use your finger to apply this medicine. Do not stop using it suddenly without talking to your doctor, as it may lead to worsening of your condition. This medicine is generally well tolerated with minimal or no side effects. However, slight anal irritation may occur as a side effect of this medicine. This is temporary and usually resolves on its own in some time. Please consult your doctor if it does not resolve or persists for a longer duration. Avoid getting it into your eyes, nose, or mouth. If accidental exposure occurs, wash your eyes with water and seek immediate medical attention. You should stop using it and inform your doctor if you notice worsening of the infection or if you develop increased redness and irritation.