Ionsmooth 5% Lotion is an antiparasitic medication. It is used to treat scabies, a condition where tiny insects infest and irritate your skin. This medicine works by killing the insects (mites) and their eggs. Your doctor will explain how to use Ionsmooth 5% Lotion and how much you need. Read the instructions that come with the medicine to make sure you use it correctly. Your skin should be clean, dry, and cool before using it. Your whole body should be washed thoroughly 8-14 hours after you have used this medicine. Most people only need to use it once to treat their condition but, if a second application is needed, wait at least 7 days. Sometimes itching may last for a few weeks after treating scabies. This is probably an allergic reaction to dead mites and not a sign that the treatment has failed. The most common side effects include mild burning, stinging, or tingling where the medicine is applied. Most side effects are usually mild and not everyone gets them. Before using it, let your doctor know if you have any skin conditions or allergies to medicines, food, or other substances, or if you have asthma. Though this medicine is generally thought to be safe, you should ask for your doctor’s advice if you are pregnant or breastfeeding.