Metacortil-C Cream is a combination of two medicines that effectively treats fungal infections of skin. It kills the fungi that cause the infection and minimizes symptoms of inflammation such as redness, swelling, and itching. Metacortil-C Cream should be used regularly to get the most benefit from it. Do not use more than you needed, it will not clear your condition faster and may only increase the side effects. Skin infections will usually get better after 2 to 6 weeks. Do not use the medicine for longer than your doctor has told you to and let him or her know if your condition does not improve after 2 weeks of treatment. The effects of medicine can be increased by keeping the affected area clean and dry, and washing hands before and after treating the infection. The most common side effects of this medicine include application site reactions like burning, irritation, itching, and redness. These are usually mild but let your doctor know if they bother you or last more than a few days. Avoid direct contact with eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water. It is not likely that other medicines you take by mouth or injection will affect the way this medicine works, but talk to your doctor before using it if you have recently used another medicine for the infection. The medicine is not recommended for pregnant women. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.