Nitrotap Applicap is a medicine used for relieving the pain associated with anal fissures (tear in the lining of the anus). It works by relaxing and widening blood vessels so blood can flow more easily. This improves blood flow and reduces the pressure in anal tissues. Nitrotap Applicap promotes healing of fissures and provides pain relief. It is for external use only. It is advised to use it in the dose and duration as advised by your doctor. Clean and dry the affected area and gently apply it over the affected area. This medicine is generally well tolerated with minimal or no side effects. However, slight anal irritation may occur as a side effect of this medicine. This is temporary and usually resolves on its own in some time. Please consult your doctor if it does not resolve or persists for a longer duration. Do not use Nitrotap Applicap if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.