Olkem 40 AM Tablet contains two medicines, both of which help to control high blood pressure. Lowering blood pressure helps to reduce your risk of having a heart attack or a stroke in the future. Olkem 40 AM Tablet may be taken on an empty stomach or along with food. However, it is better to take it regularly at a fixed time each day, as prescribed by your doctor. The dose will depend on your condition and how you respond to the medicine. It is important to keep taking this medicine even if you feel well. By lowering your blood pressure, it is reducing your risk of heart attack or stroke so do not stop taking it unless your doctor tells you to. You can help this medication work better by making a few changes to your lifestyle by being active, stopping smoking and eating low salt and low-fat diet. The most common side effects of this medicine include swelling in your ankles or feet (edema), sleepiness, dizziness, headache, taste change, upset stomach, and tiredness. Since it may cause sleepiness and dizziness, do not drive or do anything requiring concentration until you know how it affects you. Talk to your doctor if any of the side effects bother you or do not go away. Before taking this medicine, let your doctor know if you have any kidney or liver problems or severe dehydration. Pregnant or breastfeeding women should also consult their doctor before taking it. While using this medicine, your blood pressure will be monitored regularly and your kidney function may also need to be tested.