Picodril Oral Suspension is a medicine used to treat constipation. It is a laxative and helps you empty your bowels. It works by increasing movement in the intestine and provides relief from constipation. Picodril Oral Suspension should be taken in a dose as advised by your doctor. Take it at a fixed time at night. You should not use this medicine for more than a few days unless your doctor tells you to. Some lifestyle changes can help with constipation, for example eating more fiber in foods such as fruit, vegetables, and cereals, drinking plenty of fluids, and taking regular exercise. The most common side effects of taking this medicine are nausea, vomiting, and headache. These are usually mild and go away after a couple of days. If they persist, your doctor may suggest ways of preventing or reducing them. Before using this medicine you should tell your doctor if you have a blockage in your bowel, upset stomach or your bowel movements have been different for more than two weeks.