Polo 40mg Injection is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. Polo 40mg Injection is given under the supervision of a healthcare professional. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms. The most common side effects of this medicine include weight gain, sleepiness, orthostatic hypotension, and elevated plasma prolactin levels. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. As this medicine can cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. You can manage weight gain caused due to this medicine by modifying your lifestyle such as having a healthy diet and exercising regularly. You should be cautious as in rare cases it may cause serious side effects like very high blood sugar levels or seizures. Thus, regular monitoring of blood sugar levels can be useful to avoid such effects.