Prestpil Plus 0.5mg/10mg Tablet is a prescription medicine used to treat depression. It is a combination medicine that calms the brain by decreasing the abnormal and excessive activity of the nerve cells. It also increases the level of chemical messenger in the brain which improves mood. Prestpil Plus 0.5mg/10mg Tablet can be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as this may cause withdrawal symptoms. Some common side effects of this medicine include nausea, vomiting, diarrhea, confusion, memory impairment, low sexual desire, and delayed ejaculation. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Remember to inform your doctor if you develop any unusual changes in mood as it can cause suicidal thoughts and can be dangerous for you. This medicine may cause weight gain and to control it, you should have a balanced diet and exercise regularly. Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.