Protamine Sulphate 10mg Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding. Protamine Sulphate 10mg Injection is generally administered by a healthcare professional. You should not self administer this medicine. Inform your doctor if you have undergone heart surgery, have had a vasectomy, have diabetes, have received protamine insulin, or allergic to fish. Using of Protamine Sulphate 10mg Injection can cause few side effects such as decreasing your blood pressure, slow heart rate, or reactions at the site of injection. It is important to monitor the clotting levels if you are receiving multiple doses or prolonged administration of protamine.