Retino AC Gel is a combination of two medicines, used to treat acne, which appears as spots or pimples on your face, chest, or back. This medicine works by attacking the germs that cause them and rejuvenates sun-damaged skin. Retino AC Gel is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. It should not be applied to broken or damaged skin. Avoid contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get it in these areas. It may take several weeks for your symptoms to improve, but you should keep using this medicine regularly. Do not stop using it as soon as your acne starts to get better. Ask your doctor when you should stop treatment. Side effects like burning sensation, irritation, itching, redness, dryness, skin peeling, or skin inflammation (dermatitis) may be seen at the application site, in some people. These are usually temporary and resolve on their own. Consult your doctor if they bother you or do not go away. It is a safe medicine, but you should inform your doctor if you have any problems with your bowels (intestines), if you have ever had bloody diarrhea caused by taking antibiotics or if you are using any other medicines to treat skin conditions. Consult your doctor about using this medicine if you are pregnant or breastfeeding.