Shibo-Sys ET Tablet is a combination medicine used in the treatment of heavy menstrual bleeding. It works by preventing the breakdown of blood clots and controls excessive bleeding. It also increases the ability of platelets to stick together and form blood clots. You can take Shibo-Sys ET Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor. The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods. Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine.