Thiotal 500mg Injection is used for producing general anesthesia. It may also be used to reduce intracranial pressure. Thiotal 500mg Injection is given as an injection in hospital settings under the supervision of a healthcare professional. It is important to provide medical history and inform your doctor if you are suffering from cardiovascular disease, asthma, or myasthenia gravis as special care is needed in administering this medicine to such patients. Some common side effects of this medicine are skin rash or pain at the site of injection, nausea, vomiting, diarrhea, and vertigo. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus. You should avoid drinking alcohol or taking other medications that cause drowsiness after taking this medicine as it may result in serious effects. Ensure that you practice additional pregnancy control methods as this medicine may decrease the effectiveness of birth control pills.