Tolsum AP 100mg/325mg/150mg Tablet is a pain-relieving medicine. It is used in the treatment of muscle pain. It works by blocking the release of certain chemical messengers that cause pain and inflammation. Tolsum AP 100mg/325mg/150mg Tablet can be taken with or without food. Take this medicine in the dose and duration as advised by your doctor. This medicine should be taken at the same time each day to get the maximum benefit. You should keep taking this medicine for as long as your doctor recommends. The most common side effects of this medicine include nausea, vomiting, heartburn, loss of appetite, and diarrhea. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing them. Do not drive if you experience dizziness. Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any problems with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking to make sure it is safe for you. Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive dizziness and chances of liver damage.