Uphold Tablet is a combination of two medicines used in the treatment of premature ejaculation in adult men. It increases blood flow to the penis to help men get an erection. This medicine should be used only when prescribed by a doctor. Uphold Tablet works by helping to relax the blood vessels in your penis, allowing blood to flow into your penis when you get sexually excited. It may be taken with or without food. Take it as advised by your doctor, before having sexual activity. Some common side effects of this medicine include nausea, vomiting, indigestion, headache, flushing (sense of warmth in the face, ears, neck, and trunk), nosebleeds, and dry mouth. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It should be used with caution in patients with a history of seizures, depression, and other psychiatric disorders. Before you take this medicine, let your doctor also know if you have any history of heart, kidney, or liver diseases.